BDBM50042847 CHEMBL3098602
SMILES ONC(=O)CCCCC[C@H](NC(=O)[C@H]1CCC(=O)N1)C(=O)Nc1cccc(c1)C(F)(F)F
InChI Key InChIKey=XVGBJXUAVWXLJX-UHFFFAOYSA-N
Data 14 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50042847
Affinity DataIC50: 8nMAssay Description:Inhibition of human HDAC2 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human HDAC3 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human HDAC6 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of human HDAC8 using RHK(Ac)K(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Human)
R&D Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
R&D Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human HDAC10 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of human HDAC11 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human HDAC1 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
University of Siena
Curated by ChEMBL
University of Siena
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human HDAC3/NCOR2 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of human HDAC8 using RHK(Ac)K(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human HDAC2 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human HDAC1 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Human)
R&D Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
R&D Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human HDAC10 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of human HDAC11 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human HDAC6 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair