BDBM50041428 CHEMBL3356855

SMILES COc1cccc(OC)c1-c1nc(nc2ccc(Cl)cc12)C(=O)N[C@@H](C1CCCCC1)C(O)=O

InChI Key InChIKey=MIUILTGHMZTVGS-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50041428   

TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50041428(CHEMBL3356855)
Affinity DataIC50: 1.07E+3nMAssay Description:Antagonist activity at rat neurotensin receptor type 2 expressed in CHOK1 cells assessed as inhibition of SR142948a-induced calcium release by FLIPR ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50041428(CHEMBL3356855)
Affinity DataEC50: >10nMAssay Description:Agonist activity at rat neurotensin receptor type 2 expressed in CHOK1 cells assessed as increase in calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeurotensin receptor type 1(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50041428(CHEMBL3356855)
Affinity DataKi: >25nMAssay Description:Displacement of [125L]NT from rat neurotensin receptor type 1 expressed in CHOK1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeurotensin receptor type 2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50041428(CHEMBL3356855)
Affinity DataKi:  474nMAssay Description:Displacement of [125L]NT from rat neurotensin receptor type 2 expressed in CHOK1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed