BDBM50041261 ((S)-1-Methyl-2-phenyl-ethyl)-(3-phenyl-propyl)-amine::CHEMBL20337::US11999676, Compound 6

SMILES C[C@@H](Cc1ccccc1)NCCCc1ccccc1

InChI Key InChIKey=CYWPIEBWQAZHQX-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50041261   

TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50041261(((S)-1-Methyl-2-phenyl-ethyl)-(3-phenyl-propyl)-am...)
Affinity DataKi:  10.8nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50041261(((S)-1-Methyl-2-phenyl-ethyl)-(3-phenyl-propyl)-am...)
Affinity DataKi:  22nMAssay Description:Binding affinity towards sigma opioid receptor in guinea pig cerebral homogenate using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50041261(((S)-1-Methyl-2-phenyl-ethyl)-(3-phenyl-propyl)-am...)
Affinity DataKi:  22nMAssay Description:Inhibition of [3H]DTG binding to Sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandPNGBDBM50041261(((S)-1-Methyl-2-phenyl-ethyl)-(3-phenyl-propyl)-am...)
Affinity DataKi:  65nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandPNGBDBM50041261(((S)-1-Methyl-2-phenyl-ethyl)-(3-phenyl-propyl)-am...)
Affinity DataKi:  750nMAssay Description:Synaptic vesicles were prepared from rat brain using a modification of a previously described procedure (Teng et al., 1998). Briefly, fresh whole bra...More data for this Ligand-Target Pair
In DepthDetails
US Patent