BDBM50041113 2-(3-Methoxy-phenyl)-1H-quinolin-4-one::CHEMBL276340

SMILES COc1cccc(c1)-c1cc(O)c2ccccc2n1

InChI Key InChIKey=NINMRZJWLHKQKT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50041113   

TargetTubulin beta-2B chain(Bovine)
School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041113(2-(3-Methoxy-phenyl)-1H-quinolin-4-one | CHEMBL276...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-2B chain(Bovine)
School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50041113(2-(3-Methoxy-phenyl)-1H-quinolin-4-one | CHEMBL276...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50041113(2-(3-Methoxy-phenyl)-1H-quinolin-4-one | CHEMBL276...)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50041113(2-(3-Methoxy-phenyl)-1H-quinolin-4-one | CHEMBL276...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization (ITP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed