BDBM50040856 CHEMBL3353208::US9169260, 321

SMILES Cc1ccc(nc1)-n1nc(cc1NC(=O)c1cnn2cccnc12)N1CCN(CC1)C1CCOCC1

InChI Key InChIKey=KFGPSRYBPKAUNB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50040856   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50040856(US9169260, 321 | CHEMBL3353208)
Affinity DataIC50: 100nMpH: 7.2Assay Description:The kinase activity of IRAK-4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2016
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50040856(US9169260, 321 | CHEMBL3353208)
Affinity DataIC50: 100nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed