BDBM50040609 (R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl)-2-{(S)-3-methyl-1-[(S)-3-methyl-1-(2-morpholin-4-yl-ethylcarbamoyl)-butylcarbamoyl]-butylamino}-butyric acid::CHEMBL161572

SMILES CC(C)C[C@H](N[C@H](CCN1C(=O)c2cc3ccccc3cc2C1=O)C(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCCN1CCOCC1

InChI Key InChIKey=OVKVSVACJPYFHM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50040609   

TargetMatrix metalloproteinase-9(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040609((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...)
Affinity DataIC50: 13nMAssay Description:Activity against human gelatinase (MMP-9).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040609((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...)
Affinity DataIC50: 44nMAssay Description:Activity against human collagenase (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040609((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...)
Affinity DataIC50: 121nMAssay Description:Activity against human stromelysin (MMP-3).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed