BDBM50040291 CHEMBL316267::Dimethyl-(1-phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine

SMILES CN(C)[C@H]1CCc2ccccc2[C@H]1c1ccccc1

InChI Key InChIKey=NLOSPVRQRDAXEJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50040291   

TargetSigma non-opioid intracellular receptor 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040291(Dimethyl-(1-phenyl-1,2,3,4-tetrahydro-naphthalen-2...)
Affinity DataIC50: 954nMAssay Description:The compound was tested for affinity towards sigma-3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040291(Dimethyl-(1-phenyl-1,2,3,4-tetrahydro-naphthalen-2...)
Affinity DataIC50: 3.34E+3nMAssay Description:Binding affinity against sigma receptor from guinea pig brain (minus cerebellum) homogenates, using [3H]ditolylguanidine (DTG) as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040291(Dimethyl-(1-phenyl-1,2,3,4-tetrahydro-naphthalen-2...)
Affinity DataIC50: 954nMAssay Description:The compound was tested for affinity towards sigma-3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040291(Dimethyl-(1-phenyl-1,2,3,4-tetrahydro-naphthalen-2...)
Affinity DataIC50: 2.76E+3nMAssay Description:Binding affinity against sigma receptor from guinea pig brain (minus cerebellum) homogenates, using the novel [3H]-(+/-)-4 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed