BDBM50038840 (4R)-2-[(4-bromo-2-fluorophenyl)methyl]-2,3-dihydro-1H-spiro[isoquinoline-4,3'-pyrrolidine]-1,2',3,5'-tetrone::CHEMBL64091

SMILES Fc1cc(Br)ccc1CN1C(=O)c2ccccc2[C@@]2(CC(=O)NC2=O)C1=O

InChI Key InChIKey=KJPABNWHOUDAIW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038840   

TargetAldo-keto reductase family 1 member B1 [K65Q](Bovine)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50038840((4R)-2-[(4-bromo-2-fluorophenyl)methyl]-2,3-dihydr...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of aldose reductase activity in a partially purified bovine lens preparationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed