BDBM50037950 1-fluoro-4-[2-(4-methylsulfonylphenyl)-4,4-di(trifluoromethyl)-1-cyclopentenyl]benzene::1-fluoro-4-[2-[4-(methylsulfonyl)phenyl]-4,4-bis(trifluoromethyl)cyclopent-1-en-1-yl]benzene::CHEMBL111045

SMILES CS(=O)(=O)c1ccc(cc1)C1=C(CC(C1)(C(F)(F)F)C(F)(F)F)c1ccc(F)cc1

InChI Key InChIKey=USCBGKVVARTODT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50037950   

TargetProstaglandin G/H synthase 1(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037950(1-fluoro-4-[2-[4-(methylsulfonyl)phenyl]-4,4-bis(t...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037950(1-fluoro-4-[2-[4-(methylsulfonyl)phenyl]-4,4-bis(t...)
Affinity DataIC50: 67nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037950(1-fluoro-4-[2-[4-(methylsulfonyl)phenyl]-4,4-bis(t...)
Affinity DataIC50: 67.6nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed