BDBM50037222 CHEMBL321612::Cyclopropanecarboxylic acid [2-(5-methoxy-benzo[b]thiophen-3-yl)-ethyl]-amide

SMILES COc1ccc2scc(CCNC(=O)C3CC3)c2c1

InChI Key InChIKey=LLQOSVBXLRZEOL-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50037222   

TargetMelatonin receptor type 1A(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50037222(Cyclopropanecarboxylic acid [2-(5-methoxy-benzo[b]...)
Affinity DataIC50: 3.98nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50037222(Cyclopropanecarboxylic acid [2-(5-methoxy-benzo[b]...)
Affinity DataKd:  1.90nMAssay Description:Binding affinity to melatonin receptor measured on ovine pars tuberalis membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
Institut De Chimie Pharmaceutique

Curated by ChEMBL
LigandPNGBDBM50037222(Cyclopropanecarboxylic acid [2-(5-methoxy-benzo[b]...)
Affinity DataIC50: 4nMAssay Description:Monophasic inhibitory concentration against melatonin receptor was measured on ovine pars tuberalis membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed