BDBM50036850 8-{4-[(5-Hydroxy-chroman-3-yl)-propyl-amino]-butyl}-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL27763

SMILES CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(O)c2C1

InChI Key InChIKey=SWQROGXQGSMWNA-UHFFFAOYSA-N

Data  2 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50036850   

TargetAlpha-1A adrenergic receptor(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036850(8-{4-[(5-Hydroxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against alpha-1 adrenergic receptor in calf frontal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036850(8-{4-[(5-Hydroxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 1nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A (5-HT1A) receptor in rat hippocampus membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036850(8-{4-[(5-Hydroxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 3.00E+4nMAssay Description:Binding affinity for 5-hydroxytryptamine 1B receptor in rat cortex, striatum and globus pallidusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036850(8-{4-[(5-Hydroxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 4.00E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor in calf frontal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036850(8-{4-[(5-Hydroxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity towards dopamine receptor D1 in calf striatumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036850(8-{4-[(5-Hydroxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 8nMAssay Description:Binding affinity against D2 receptor in calf caudate nucleusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036850(8-{4-[(5-Hydroxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Binding affinity against alpha-2 adrenergic receptor in calf frontal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036850(8-{4-[(5-Hydroxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataKi:  0.501nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50036850(8-{4-[(5-Hydroxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataKi:  0.501nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed