BDBM50036785 1'-(2-naphthylmethyl)spiro[1,2,3,4-tetrahydronaphthalene-2,4'-(hexahydropyridine)]-1-one ;malate::CHEMBL123937

SMILES O=C1c2ccccc2CCC11CCN(Cc2ccc3ccccc3c2)CC1

InChI Key InChIKey=ZYQPFSVYWPFCAH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036785   

TargetSigma non-opioid intracellular receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036785(1'-(2-naphthylmethyl)spiro[1,2,3,4-tetrahydronapht...)
Affinity DataKi:  11nMAssay Description:Binding affinity for sigma receptor of guinea pig whole brain using [3H]-SKF- 100047 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036785(1'-(2-naphthylmethyl)spiro[1,2,3,4-tetrahydronapht...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for dopamine D2 receptor using [3H]spiperone in guinea pig striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed