BDBM50036769 1'-[4-(4-fluorophenyl)-4-oxobutyl]-3,4-dihydro-1H-spiro[naphthalene-2,4'-piperidine]-1-one chloride::CHEMBL554873

SMILES O=C1c2ccccc2CCC11CCN(CCc2ccccc2)CC1

InChI Key InChIKey=RGHKOAFUHZEYJM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036769   

TargetSigma non-opioid intracellular receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036769(1'-[4-(4-fluorophenyl)-4-oxobutyl]-3,4-dihydro-1H-...)
Affinity DataKi:  56nMAssay Description:Binding affinity for sigma receptor of guinea pig whole brain using [3H]-SKF- 100047 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036769(1'-[4-(4-fluorophenyl)-4-oxobutyl]-3,4-dihydro-1H-...)
Affinity DataKi:  2.19E+3nMAssay Description:Binding affinity for dopamine D2 receptor using [3H]spiperone in guinea pig striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed