BDBM50036764 1'-benzylspiro[1,2,3,4-tetrahydronaphthalene-2,4'-(hexahydropyridine)]-1-one; hydrochloride::CHEMBL41830::CHEMBL554874

SMILES O=C1c2ccccc2CCC11CCN(Cc2ccccc2)CC1

InChI Key InChIKey=PZWPPSAANHYITK-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50036764   

TargetSigma non-opioid intracellular receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036764(CHEMBL41830 | CHEMBL554874 | 1'-benzylspiro[1,2,3,...)
Affinity DataKi:  1nMAssay Description:Binding affinity for sigma receptor of guinea pig whole brain using [3H]-SKF- 100047 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036764(CHEMBL41830 | CHEMBL554874 | 1'-benzylspiro[1,2,3,...)
Affinity DataKi:  1.40nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H](+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50036764(CHEMBL41830 | CHEMBL554874 | 1'-benzylspiro[1,2,3,...)
Affinity DataKi:  2.70E+3nMAssay Description:Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M2 using [3H]NMS from rat heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036764(CHEMBL41830 | CHEMBL554874 | 1'-benzylspiro[1,2,3,...)
Affinity DataKi:  3.51E+3nMAssay Description:Binding affinity for dopamine D2 receptor using [3H]spiperone in guinea pig striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50036764(CHEMBL41830 | CHEMBL554874 | 1'-benzylspiro[1,2,3,...)
Affinity DataKi:  5.50E+3nMAssay Description:Compound was tested for its binding affinity towards Dopamine receptor D2 using [3H]spiperone from rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50036764(CHEMBL41830 | CHEMBL554874 | 1'-benzylspiro[1,2,3,...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Alpha-1B adrenergic receptor using [3H]prazosin from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50036764(CHEMBL41830 | CHEMBL554874 | 1'-benzylspiro[1,2,3,...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Alpha-1A adrenergic receptor using [3H]prazosin from rat submaxillary glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50036764(CHEMBL41830 | CHEMBL554874 | 1'-benzylspiro[1,2,3,...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M3 using [3H]NMS from rat submaxillary glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50036764(CHEMBL41830 | CHEMBL554874 | 1'-benzylspiro[1,2,3,...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards PCP receptor using [3H](+)-NANM in the presence of 5 uM haloperidol from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed