BDBM50036712 4-(4-Chloro-phenyl)-1,2,3,6-tetrahydro-pyridine::CHEMBL101664::CHEMBL2011566

SMILES Clc1ccc(cc1)C1=CCNCC1

InChI Key InChIKey=SXOMHACGFSJBIO-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50036712   

TargetSigma non-opioid intracellular receptor 1(Human)
New York University

Curated by ChEMBL
LigandPNGBDBM50036712(CHEMBL101664 | CHEMBL2011566 | 4-(4-Chloro-phenyl)...)
Affinity DataIC50: 50nMAssay Description:Binding affinity against sigma receptor in bovine cerebellum using 2.0 nM [3H]haloperidol in the presence of 25 nM unlabeled spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
New York University

Curated by ChEMBL
LigandPNGBDBM50036712(CHEMBL101664 | CHEMBL2011566 | 4-(4-Chloro-phenyl)...)
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity against Dopamine receptor D2 in bovine striatal homogenate using 200 pM [3H]- spiperone and 250 nM unlabeled ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50036712(CHEMBL101664 | CHEMBL2011566 | 4-(4-Chloro-phenyl)...)
Affinity DataEC50:  1.76E+3nMAssay Description:Agonist activity at 5HT2C receptor expressed in CHO cells by fluorescence based calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50036712(CHEMBL101664 | CHEMBL2011566 | 4-(4-Chloro-phenyl)...)
Affinity DataKi:  3.10E+3nMAssay Description:Displacement of [3H]-mesulergine from 5HT2C receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed