BDBM50036695 2-[5-(2,2-Dicyano-vinyl)-2-hydroxy-3-methoxy-benzylsulfanyl]-benzoic acid::2-[5-(2,2-Dicyano-vinyl)-2-hydroxy-3-methoxy-benzylsulfanyl]-benzoic acid anion::CHEMBL118321

SMILES [#6]-[#8]-c1cc(\[#6]=[#6](/C#N)C#N)cc(-[#6]-[#16]-c2ccccc2-[#6](-[#8])=O)c1-[#8]

InChI Key InChIKey=CSEQWRPKHRIRAT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50036695   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036695(2-[5-(2,2-Dicyano-vinyl)-2-hydroxy-3-methoxy-benzy...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory concentration against EGF receptor by autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036695(2-[5-(2,2-Dicyano-vinyl)-2-hydroxy-3-methoxy-benzy...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibitory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036695(2-[5-(2,2-Dicyano-vinyl)-2-hydroxy-3-methoxy-benzy...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HER-14 (human EGFR overexpressing NIH3T3) cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036695(2-[5-(2,2-Dicyano-vinyl)-2-hydroxy-3-methoxy-benzy...)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibitory activity against epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50036695(2-[5-(2,2-Dicyano-vinyl)-2-hydroxy-3-methoxy-benzy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity tested against protein kinase HER-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Human)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036695(2-[5-(2,2-Dicyano-vinyl)-2-hydroxy-3-methoxy-benzy...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory concentration against ErbB2/neu (HER-2) by autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed