BDBM50036682 CHEMBL120719::[5-(2,2-Dicyano-vinyl)-2-hydroxy-3-methoxy-benzylsulfanyl]-acetic acid

SMILES [#6]-[#8]-c1cc(\[#6]=[#6](/C#N)C#N)cc(-[#6]-[#16]-[#6]-[#6](-[#8])=O)c1-[#8]

InChI Key InChIKey=KCNVPMBDBWRFEN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50036682   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036682([5-(2,2-Dicyano-vinyl)-2-hydroxy-3-methoxy-benzyls...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HER-14 (human EGFR overexpressing NIH3T3) cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Human)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036682([5-(2,2-Dicyano-vinyl)-2-hydroxy-3-methoxy-benzyls...)
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibitory concentration against ErbB2/neu (HER-2) by autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036682([5-(2,2-Dicyano-vinyl)-2-hydroxy-3-methoxy-benzyls...)
Affinity DataIC50: 9.60E+4nMAssay Description:Inhibitory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036682([5-(2,2-Dicyano-vinyl)-2-hydroxy-3-methoxy-benzyls...)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibitory concentration against EGF receptor by autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed