BDBM50036294 CHEMBL3353063

SMILES Cn1cccc1C(=O)N1CCn2nc(cc2C1)C(=O)NO

InChI Key InChIKey=KMSICMDUXFRYHT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036294   

TargetHistone deacetylase 6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036294(CHEMBL3353063)
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant N-GST-tagged HDAC6 (unknown origin) assessed as reduction in deacetylation of Ac-Arg-Gly-Lys(Ac)-AMC substrate by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036294(CHEMBL3353063)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of HDAC6 in human HeLa cells assessed as reduction in K40 hyperacetylation of alpha-tubulin incubated for 6 hrs by immunofluorescence assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed