BDBM50035880 CHEMBL1437990

SMILES Nc1nc(SCCc2ccccc2)c2nc[nH]c2n1

InChI Key InChIKey=PAAAKNYXXIVNCJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50035880   

TargetDNA topoisomerase 2-alpha(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50035880(CHEMBL1437990)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alpha using plasmid pNO1 substrate incubated at 37 degC for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50035880(CHEMBL1437990)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant His-tagged MTH1 expressed in Escherichia coli BL21 using dGTP as substrate after 15 mins by malachite green reagent-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed