BDBM50035787 4-Amino-5-fluoro-1-((2S,5R)-5-hydroxymethyl-tetrahydro-thiophen-2-yl)-1H-pyrimidin-2-one::CHEMBL335193

SMILES Nc1nc(=O)n(cc1F)[C@@H]1CC[C@H](CO)S1

InChI Key InChIKey=BAWRQSYFRBPSPK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035787   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Biochem Therapeutic

Curated by ChEMBL
LigandPNGBDBM50035787(4-Amino-5-fluoro-1-((2S,5R)-5-hydroxymethyl-tetrah...)
Affinity DataIC50: 250nMAssay Description:Ability to inhibit the HIV-1 reverse transcriptase in cord blood mononuclear cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed