BDBM50035279 3-Methoxy-5,6,7,8-tetrahydro-4H-isoxazolo[4,5-c]azepine::CHEMBL304142

SMILES COc1noc2CCCNCc12

InChI Key InChIKey=MMAAVQKZYQKTJY-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50035279   

TargetMuscarinic acetylcholine receptor M2(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50035279(3-Methoxy-5,6,7,8-tetrahydro-4H-isoxazolo[4,5-c]az...)
Affinity DataEC50:  43nMAssay Description:In Vitro activity at the cloned Human Muscarinic acetylcholine receptor M2 determined by receptor selection and amplification technology (R-SAT).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50035279(3-Methoxy-5,6,7,8-tetrahydro-4H-isoxazolo[4,5-c]az...)
Affinity DataEC50:  4.70E+3nMAssay Description:In Vitro activity at the cloned Human Muscarinic acetylcholine receptor M5 determined by receptor selection and amplification technology (R-SAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50035279(3-Methoxy-5,6,7,8-tetrahydro-4H-isoxazolo[4,5-c]az...)
Affinity DataEC50:  460nMAssay Description:In Vitro evaluation activity at the cloned Human Muscarinic acetylcholine receptor M1 determined by receptor selection and amplification technology (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50035279(3-Methoxy-5,6,7,8-tetrahydro-4H-isoxazolo[4,5-c]az...)
Affinity DataEC50:  240nMAssay Description:In Vitro activity at the cloned Human Muscarinic acetylcholine receptor M4 determined by receptor selection and amplification technology (R-SAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50035279(3-Methoxy-5,6,7,8-tetrahydro-4H-isoxazolo[4,5-c]az...)
Affinity DataEC50:  620nMAssay Description:In Vitro activity at the cloned Human Muscarinic acetylcholine receptor M3 determined by receptor selection and amplification technology (R-SAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed