BDBM50035209 4-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen-1-yl)-pyridine::CHEMBL304903

SMILES C1Cc2ccccc2C2C1C2c1ccncc1

InChI Key InChIKey=KNIGVLQBCXKAGG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50035209   

TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035209(4-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen...)
Affinity DataIC50: 185nMAssay Description:Inhibition of Human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
UniversitäT De Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035209(4-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen...)
Affinity DataIC50: 3.60E+4nMAssay Description:In vitro inhibitory activity against Steroidgenic Cytochrome P450 17 alpha using rat testicular microsomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035209(4-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen...)
Affinity DataIC50: 370nMAssay Description:In vitro inhibitory activity against Cytochrome P450 19A1 using human placental microsomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
UniversitäT De Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035209(4-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen...)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibitory activity against Steroidgenic Cytochrome P450 C18 using Bovine adrenal mitochondria.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Rat)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035209(4-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibition of ACTH-stimulated aldosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed