BDBM50035204 4-(6-Methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]naphthalen-1-yl)-pyridine::4-(6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]naphthalen-1-yl)pyridine::CHEMBL294361

SMILES COc1ccc2CCC3C(C3c2c1)c1ccncc1

InChI Key InChIKey=XPZLSAZRILMQEG-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50035204   

TargetCytochrome P450 11B2, mitochondrial(Rat)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035204(4-(6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of ACTH-stimulated aldosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035204(4-(6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035204(4-(6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro inhibition of ACTH-stimulated corticosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Rat)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035204(4-(6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 265nMAssay Description:In vitro inhibition of rat ovarian microsomal Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035204(4-(6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035204(4-(6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human placental aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035204(4-(6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human placental aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035204(4-(6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 61nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035204(4-(6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro inhibition of ACTH-stimulated corticosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Rat)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandPNGBDBM50035204(4-(6-methoxy-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of ACTH-stimulated aldosterone biosynthesis in rat adrenal slicesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed