BDBM50035102 1-(4-Fluoro-phenyl)-3-{4-[4-(4-fluoro-phenyl)-piperidin-1-yl]-butyl}-1H-indole::CHEMBL61539

SMILES Fc1ccc(cc1)C1CCN(CCCCc2cn(-c3ccc(F)cc3)c3ccccc23)CC1

InChI Key InChIKey=NGVLXUDHOKGWPG-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50035102   

TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035102(1-(4-Fluoro-phenyl)-3-{4-[4-(4-fluoro-phenyl)-pipe...)
Affinity DataIC50: 4.20E+3nMAssay Description:Binding affinity towards Dopamine receptor D2 binding site using [3H]spiroperidol.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035102(1-(4-Fluoro-phenyl)-3-{4-[4-(4-fluoro-phenyl)-pipe...)
Affinity DataIC50: 2.20E+4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor binding site using [3H]8-OH-DPAT. More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035102(1-(4-Fluoro-phenyl)-3-{4-[4-(4-fluoro-phenyl)-pipe...)
Affinity DataIC50: 270nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor binding site using [3H]ketanserin. More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035102(1-(4-Fluoro-phenyl)-3-{4-[4-(4-fluoro-phenyl)-pipe...)
Affinity DataIC50: 16nMAssay Description:Binding affinity towards sigma receptor binding site 1 using [3H](+)-pentazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50035102(1-(4-Fluoro-phenyl)-3-{4-[4-(4-fluoro-phenyl)-pipe...)
Affinity DataKi:  16nMAssay Description:Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed