BDBM50035101 1'-[4-(1H-3-indolyl)butyl]spiro[1,3-dihydroisobenzofuran-1,4'-(hexahydropyridine)]::CHEMBL59464

SMILES C(CCc1c[nH]c2ccccc12)CN1CCC2(CC1)OCc1ccccc21

InChI Key InChIKey=GOIYUNROIAKNAE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50035101   

Target5-hydroxytryptamine receptor 2A(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035101(1'-[4-(1H-3-indolyl)butyl]spiro[1,3-dihydroisobenz...)
Affinity DataIC50: 360nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor binding site using [3H]ketanserin. More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035101(1'-[4-(1H-3-indolyl)butyl]spiro[1,3-dihydroisobenz...)
Affinity DataIC50: 1.30E+3nMAssay Description:Binding affinity towards Dopamine receptor D2 binding site using [3H]spiroperidol.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035101(1'-[4-(1H-3-indolyl)butyl]spiro[1,3-dihydroisobenz...)
Affinity DataIC50: 130nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor binding site using [3H]8-OH-DPAT. More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035101(1'-[4-(1H-3-indolyl)butyl]spiro[1,3-dihydroisobenz...)
Affinity DataIC50: 2.5nMAssay Description:Binding affinity towards sigma receptor binding site 1 using [3H](+)-pentazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed