BDBM50033733 (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methylpent-3-enyl pentanoate::CHEMBL9499::Pentanoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)-4-methyl-pent-3-enyl ester

SMILES [#6]-[#6]-[#6]-[#6]-[#6](=O)-[#8]-[#6](=[#6]\[#6]=[#6](\[#6])-[#6])-c1cc(-[#8])c2c(-[#8])ccc(-[#8])c2c1-[#8]

InChI Key InChIKey=LKONNSDDSSRDBI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50033733   

TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033733(Pentanoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-...)
Affinity DataIC50: 1.61E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSterol O-acyltransferase 2(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033733(Pentanoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-...)
Affinity DataIC50: 8.45E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSterol O-acyltransferase 1(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033733(Pentanoic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-...)
Affinity DataIC50: 9.48E+4nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed