BDBM50033725 (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methylpent-3-enyl propionate::CHEMBL8951::Propionic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)-4-methyl-pent-3-enyl ester

SMILES [#6]-[#6]-[#6](=O)-[#8]-[#6](=[#6]\[#6]=[#6](\[#6])-[#6])-c1cc(-[#8])c2c(-[#8])ccc(-[#8])c2c1-[#8]

InChI Key InChIKey=VUKHFZHJRQOMQF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50033725   

TargetDNA topoisomerase 1(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033725(Propionic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-...)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibitory activity against DNA topoisomerase-1 obtained from Hela cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033725(Propionic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-...)
Affinity DataIC50: 2.24E+4nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50033725(Propionic acid (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-...)
Affinity DataIC50: 2.87E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed