BDBM50033680 CHEMBL268919::Sodium; (R)-3-acetoxymethyl-7-[1-tert-butoxycarbonyl-meth-(Z)-ylidene]-5,5,8-trioxo-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate

SMILES CC(=O)OCC1=C(N2[C@@H](\C(=C/C(=O)OC(C)(C)C)C2=O)S(=O)(=O)C1)C([O-])=O

InChI Key InChIKey=LQVZDTYWLLBGHZ-UHFFFAOYSA-M

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50033680   

TargetBeta-lactamase(Enterobacter cloacae)
TBA

Curated by ChEMBL
LigandPNGBDBM50033680(Sodium; (R)-3-acetoxymethyl-7-[1-tert-butoxycarbon...)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibitory activity against beta-Lactamase enzyme derived from Enterobacter cloacae P99More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetBeta-lactamase(Staphylococcus aureus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50033680(Sodium; (R)-3-acetoxymethyl-7-[1-tert-butoxycarbon...)
Affinity DataIC50: 30nMAssay Description:The compound was evaluated for inhibition against Beta-lactamase TEM derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50033680(Sodium; (R)-3-acetoxymethyl-7-[1-tert-butoxycarbon...)
Affinity DataIC50: 5nMAssay Description:The concentration of compound to inhibit beta-lactamase was measured on Escherichia coli WC3310More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Enterobacter cloacae)
TBA

Curated by ChEMBL
LigandPNGBDBM50033680(Sodium; (R)-3-acetoxymethyl-7-[1-tert-butoxycarbon...)
Affinity DataIC50: 7.80E+3nMAssay Description:The concentration of compound to inhibit beta-lactamase was measured on Enterobacter cloacae P99More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Enterobacter cloacae)
TBA

Curated by ChEMBL
LigandPNGBDBM50033680(Sodium; (R)-3-acetoxymethyl-7-[1-tert-butoxycarbon...)
Affinity DataIC50: 5.90E+3nMAssay Description:The concentration of compound to inhibit beta-lactamase was measured on Enterobacter cloacae SC 12368More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50033680(Sodium; (R)-3-acetoxymethyl-7-[1-tert-butoxycarbon...)
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of Class C beta-lactamase from Enterobacter cloacae strain P99More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50033680(Sodium; (R)-3-acetoxymethyl-7-[1-tert-butoxycarbon...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against beta-Lactamase enzyme derived from Escherichia coli WC3310 TEM-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetBeta-lactamase(Staphylococcus aureus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50033680(Sodium; (R)-3-acetoxymethyl-7-[1-tert-butoxycarbon...)
Affinity DataIC50: 9.77E+5nMAssay Description:The compound was evaluated for inhibition against Beta-lactamase derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Enterobacter cloacae)
TBA

Curated by ChEMBL
LigandPNGBDBM50033680(Sodium; (R)-3-acetoxymethyl-7-[1-tert-butoxycarbon...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibitory activity against beta-Lactamase enzyme derived from Enterobacter cloacae SC 12368 E-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article