BDBM50033378 CHEMBL3357647

SMILES CCOc1cc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(Cl)c3)c2cc1NC(=O)C(\F)=C\CN1CCCCC1

InChI Key InChIKey=GYFJBUOSPWKVQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50033378   

TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50033378(CHEMBL3357647)
Affinity DataIC50: 38nMAssay Description:Inhibition of wild type EGFR T790M mutant (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50033378(CHEMBL3357647)
Affinity DataIC50: 13nMAssay Description:Inhibition of wild type EGFR (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed