BDBM50033067 4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-[1,3]dithiolan-2-yl]-benzoic acid::CHEMBL323626

SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C1(SCCS1)c1ccc(cc1)C(O)=O

InChI Key InChIKey=NWFLPURWUQNLIV-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50033067   

TargetRetinoic acid receptor RXR-alpha(Human)
Sri International

Curated by ChEMBL
LigandPNGBDBM50033067(4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  170nMAssay Description:Effective concentration against Retinoic acid receptor RXR-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50033067(4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50033067(4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed