BDBM50031871 5-Chloro-6-[(3,4,5-trimethoxy-phenylamino)-methyl]-quinazoline-2,4-diamine::CHEMBL88555

SMILES COc1cc(NCc2ccc3nc(N)nc(N)c3c2Cl)cc(OC)c1OC

InChI Key InChIKey=NSEUBMXNDPFXNO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50031871   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute

Curated by ChEMBL
LigandPNGBDBM50031871(5-Chloro-6-[(3,4,5-trimethoxy-phenylamino)-methyl]...)
Affinity DataIC50: 5.20nMAssay Description:Concentration inhibiting Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute

Curated by ChEMBL
LigandPNGBDBM50031871(5-Chloro-6-[(3,4,5-trimethoxy-phenylamino)-methyl]...)
Affinity DataIC50: 33nMAssay Description:Concentration inhibiting Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Rat)
Institute

Curated by ChEMBL
LigandPNGBDBM50031871(5-Chloro-6-[(3,4,5-trimethoxy-phenylamino)-methyl]...)
Affinity DataIC50: 5.90nMAssay Description:Concentration inhibiting rat liver dihydrofolate reductase. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute

Curated by ChEMBL
LigandPNGBDBM50031871(5-Chloro-6-[(3,4,5-trimethoxy-phenylamino)-methyl]...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of Dihydrofolate reductase of Toxoplasma gondiiMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute

Curated by ChEMBL
LigandPNGBDBM50031871(5-Chloro-6-[(3,4,5-trimethoxy-phenylamino)-methyl]...)
Affinity DataIC50: 33nMAssay Description:Inhibition of Dihydrofolate reductase of Pneumocystis cariniiMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Rat)
Institute

Curated by ChEMBL
LigandPNGBDBM50031871(5-Chloro-6-[(3,4,5-trimethoxy-phenylamino)-methyl]...)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of Dihydrofolate reductase (DHFR) of in rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed