BDBM50031868 6-((3,4,5-trimethoxyphenylamino)methyl)pyrido[3,2-d]pyrimidine-2,4-diamine::6-[(3,4,5-Trimethoxy-phenylamino)-methyl]-pyrido[3,2-d]pyrimidine-2,4-diamine::CHEMBL55179

SMILES COc1cc(NCc2ccc3nc(N)nc(N)c3n2)cc(OC)c1OC

InChI Key InChIKey=ASYMVCBDRFSMND-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50031868   

TargetDihydrofolate reductase(Pneumocystis carinii)
Institute

Curated by ChEMBL
LigandPNGBDBM50031868(6-[(3,4,5-Trimethoxy-phenylamino)-methyl]-pyrido[3...)
Affinity DataIC50: 2.60E+3nMAssay Description:Concentration inhibiting Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute

Curated by ChEMBL
LigandPNGBDBM50031868(6-[(3,4,5-Trimethoxy-phenylamino)-methyl]-pyrido[3...)
Affinity DataIC50: 82nMAssay Description:Concentration inhibiting Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Institute

Curated by ChEMBL
LigandPNGBDBM50031868(6-[(3,4,5-Trimethoxy-phenylamino)-methyl]-pyrido[3...)
Affinity DataIC50: 300nMAssay Description:Concentration inhibiting rat liver dihydrofolate reductase. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Baker's yeast)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50031868(6-[(3,4,5-Trimethoxy-phenylamino)-methyl]-pyrido[3...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute

Curated by ChEMBL
LigandPNGBDBM50031868(6-[(3,4,5-Trimethoxy-phenylamino)-methyl]-pyrido[3...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Institute

Curated by ChEMBL
LigandPNGBDBM50031868(6-[(3,4,5-Trimethoxy-phenylamino)-methyl]-pyrido[3...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Institute

Curated by ChEMBL
LigandPNGBDBM50031868(6-[(3,4,5-Trimethoxy-phenylamino)-methyl]-pyrido[3...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Institute

Curated by ChEMBL
LigandPNGBDBM50031868(6-[(3,4,5-Trimethoxy-phenylamino)-methyl]-pyrido[3...)
Affinity DataIC50: 200nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute

Curated by ChEMBL
LigandPNGBDBM50031868(6-[(3,4,5-Trimethoxy-phenylamino)-methyl]-pyrido[3...)
Affinity DataIC50: 40nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed