BDBM50030743 CHEMBL1506885

SMILES O=C(NCCCN1CCOCC1)c1cnn2c(cc(nc12)-c1ccccc1)-c1ccccc1

InChI Key InChIKey=JTRXWCLQFAZHGP-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50030743   

TargetMultidrug resistance-associated protein 1(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50030743(CHEMBL1506885)
Affinity DataEC50:  9.80E+3nMAssay Description:Modulation of MRP1 mediated drug efflux in doxorubicin-resistant human H69 cells assessed as accumulation of calcein AM incubated for 15 mins prior t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMultidrug resistance-associated protein 1(Human)
Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50030743(CHEMBL1506885)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human MRP1 transfected in MDCK2 cells assessed as inhibition of calcein-AM effluxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50030743(CHEMBL1506885)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of ABCB1 in human KBV1 cells assessed as inhibition of calcein-AM effluxMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed