BDBM50030149 CHEMBL3343531

SMILES NC(=O)c1cncc(Sc2cccc3ccccc23)c1

InChI Key InChIKey=SANGKCYTAMNMIW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50030149   

TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50030149(CHEMBL3343531)
Affinity DataIC50: 3.01E+4nMAssay Description:Inhibition of catalytically active human SIRT3 (102 to 399 amino acids) expressed in Escherichia coli BL21 (DE3) cells using fluorogenic 7-amino-4-me...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50030149(CHEMBL3343531)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of full length human SIRT2 expressed in Escherichia coli BL21 (DE3) cells using fluorogenic 7-amino-4-methylcoumarin (AMC)-labeled peptide...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50030149(CHEMBL3343531)
Affinity DataIC50: 3.03E+4nMAssay Description:Inhibition of full length human SIRT1 expressed in Escherichia coli BL21 (DE3) cells using fluorogenic 7-amino-4-methylcoumarin (AMC)-labeled peptide...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed