BDBM50029512 CHEMBL139910::tert-butyloxy carbonyl-D-Phe-DL-Pro(5,5-methyl)-Arg-H

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N1C(CCC1(C)C)C(=O)N[C@@H](CCCNC(N)=N)C=O

InChI Key InChIKey=LXGQREKZSPKHGU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50029512   

TargetPlasminogen(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029512(tert-butyloxy carbonyl-D-Phe-DL-Pro(5,5-methyl)-Ar...)
Affinity DataIC50: 1.10E+4nMAssay Description:In vitro Enzyme Inhibitory activity measured against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029512(tert-butyloxy carbonyl-D-Phe-DL-Pro(5,5-methyl)-Ar...)
Affinity DataIC50: 170nMAssay Description:In vitro Enzyme Inhibitory activity measured against TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029512(tert-butyloxy carbonyl-D-Phe-DL-Pro(5,5-methyl)-Ar...)
Affinity DataIC50: 3.00E+7nMAssay Description:In vitro Enzyme Inhibitory activity against t-PA(Tissue plasminogen activator).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029512(tert-butyloxy carbonyl-D-Phe-DL-Pro(5,5-methyl)-Ar...)
Affinity DataIC50: 1.80E+4nMAssay Description:In vitro Enzyme Inhibitory activity measured against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029512(tert-butyloxy carbonyl-D-Phe-DL-Pro(5,5-methyl)-Ar...)
Affinity DataIC50: 290nMAssay Description:In vitro Enzyme Inhibitory activity measured against ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed