BDBM50029448 3-{3-[3-(5-Ethyl-2-hydroxy-biphenyl-4-yloxy)-propoxy]-9-oxo-9H-xanthen-4-yl}-propionic acid::CHEMBL129272

SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccccc3c2=O)c1CCC(O)=O)-c1ccccc1

InChI Key InChIKey=AZXAHRBQFLYINX-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50029448   

TargetLeukotriene B4 receptor 1/2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029448(3-{3-[3-(5-Ethyl-2-hydroxy-biphenyl-4-yloxy)-propo...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of LTB4-induced up-regulation of human neutrophil CD11b/CD18 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029448(3-{3-[3-(5-Ethyl-2-hydroxy-biphenyl-4-yloxy)-propo...)
Affinity DataKi:  12nMAssay Description:Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029448(3-{3-[3-(5-Ethyl-2-hydroxy-biphenyl-4-yloxy)-propo...)
Affinity DataKi:  22nMAssay Description:Tested for inhibition of specific binding of [3H]LTB4 to human neutrophil expressing LTB4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed