BDBM50029238 CHEMBL132072::Pyridin-4-yl-acetic acid (S)-2,6,6-trimethyl-bicyclo[3.1.1]hept-3-yl ester

SMILES C[C@H]1C2CC(CC1OC(=O)Cc1ccncc1)C2(C)C

InChI Key InChIKey=FYHFPSGWNXSFBI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50029238   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029238(Pyridin-4-yl-acetic acid (S)-2,6,6-trimethyl-bicyc...)
Affinity DataIC50: 14nMAssay Description:Tested for inhibition of human testicular Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029238(Pyridin-4-yl-acetic acid (S)-2,6,6-trimethyl-bicyc...)
Affinity DataIC50: 120nMAssay Description:Tested for inhibition of human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029238(Pyridin-4-yl-acetic acid (S)-2,6,6-trimethyl-bicyc...)
Affinity DataIC50: 260nMAssay Description:Inhibition of rat testicular Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029238(Pyridin-4-yl-acetic acid (S)-2,6,6-trimethyl-bicyc...)
Affinity DataIC50: 5nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029238(Pyridin-4-yl-acetic acid (S)-2,6,6-trimethyl-bicyc...)
Affinity DataIC50: 280nMAssay Description:Inhibition of rat testicular C17,20-LyaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed