BDBM50029086 CHEMBL3360816

SMILES Cl.CCCCCC(=O)O[C@@H]1[C@@H](CSCCNC(=S)NCCN(CCN)CCN)O[C@H](OC)[C@H](OC(=O)CCCCC)[C@H]1OC(=O)CCCCC

InChI Key InChIKey=QKQGRGBGMWYFLC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50029086   

TargetToll-like receptor 4(Human)
University of Sevilla

Curated by ChEMBL
LigandPNGBDBM50029086(CHEMBL3360816)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of LPS-induced TLR4 activation (unknown origin) expressed in HEK293 Blue cells compound treated for 30 mins prior LPS treatment measured a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetToll-like receptor 4(Human)
University of Sevilla

Curated by ChEMBL
LigandPNGBDBM50029086(CHEMBL3360816)
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at human TLR4 expressed in HEK293 cells co-transfected with human MD-2/CD14 assessed as inhibition of LPS-stimulated receptor sig...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Sevilla

Curated by ChEMBL
LigandPNGBDBM50029086(CHEMBL3360816)
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at mouse TLR4 expressed in HEK293 cells co-transfected with mouse MD-2/CD14 assessed as inhibition of LPS-stimulated receptor sig...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed