BDBM50028180 CHEMBL3354625

SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(c(F)c1)-c1ccccc1

InChI Key InChIKey=IRIRASPSMMWZOM-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50028180   

TargetCeramide glucosyltransferase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028180(CHEMBL3354625)
Affinity DataIC50: 25nMAssay Description:Inhibition of glucosylceramide synthase (unknown origin) assessed as catabolism of NBD-glucosylceramideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028180(CHEMBL3354625)
Affinity DataIC50: 200nMAssay Description:Inhibition of GBA1 (unknown origin) using beta-D-[1-14C]glucocerebroside assessed as 4-methylumbelliferrone by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028180(CHEMBL3354625)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028180(CHEMBL3354625)
Affinity DataIC50: 400nMAssay Description:Inhibition of intestinal sucrase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
TargetLactase/phlorizin hydrolase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028180(CHEMBL3354625)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of intestinal lactase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
TargetMaltase-glucoamylase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028180(CHEMBL3354625)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of intestinal maltase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed