BDBM50027664 CHEMBL3338404

SMILES ONC(=O)c1ccc2CCN(Cc3ccc(o3)-c3cccc(c3)[N+]([O-])=O)Cc2c1

InChI Key InChIKey=PMFDRULHDRRWFP-UHFFFAOYSA-N

Data  11 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50027664   

TargetHistone deacetylase 6(Human)
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataEC50:  3.45E+3nMAssay Description:Inhibition of HDAC6 in human A549 cells assessed as tubulin acetylation after 17 to 18 hrs by cytoblot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50: 2.13E+4nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50: 1.09E+5nMAssay Description:Inhibition of HDAC2 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50: 6.59E+3nMAssay Description:Inhibition of HDAC3 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50: 6.78E+4nMAssay Description:Inhibition of HDAC4 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of HDAC5 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50: 50nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50: 6.07E+4nMAssay Description:Inhibition of HDAC7 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50: 30nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50: 6.58E+4nMAssay Description:Inhibition of HDAC9 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50: 7.11E+4nMAssay Description:Inhibition of HDAC10 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50027664(CHEMBL3338404)
Affinity DataIC50: 7.53E+4nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed