BDBM50027661 CHEMBL3338417

SMILES ONC(=O)c1ccc2CC[C@@H](Cc2c1)Nc1nccc(n1)-c1cccnc1

InChI Key InChIKey=MWLFQRZKKHIDTM-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50027661   

TargetHistone deacetylase 6(Human)
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50027661(CHEMBL3338417)
Affinity DataEC50:  690nMAssay Description:Inhibition of HDAC6 in human A549 cells assessed as tubulin acetylation after 17 to 18 hrs by cytoblot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50027661(CHEMBL3338417)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50027661(CHEMBL3338417)
Affinity DataIC50: 40nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Roche Pharmaceutical Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50027661(CHEMBL3338417)
Affinity DataIC50: 390nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed