BDBM50026808 CHEMBL2440341

SMILES CCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)c1ccc(\C=C(/C#N)C(=O)NC2CC2)cc1)C(N)=O

InChI Key InChIKey=IIZZPHMUHOCVEN-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50026808   

TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50026808(CHEMBL2440341)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease by homogeneous fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50026808(CHEMBL2440341)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease preincubated for 15 mins followed by Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr addition and measured...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50026808(CHEMBL2440341)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of Dengue virus 2 NS2B-NS3 protease using Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr as substrate preincubated for 15 mins followed by addition of...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50026808(CHEMBL2440341)
Affinity DataKi:  9.25E+4nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease preincubated for 15 mins followed by Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr addition and measured for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(WNV)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50026808(CHEMBL2440341)
Affinity DataKi:  9.25E+4nMAssay Description:Mixed type inhibition of West Nile virus NSB2-NS3 protease using Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr as substrate preincubated with compound for 15 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed