BDBM50025988 1-(2-Phenoxy-ethyl)-1H-imidazole::CHEMBL284827

SMILES C(Cn1ccnc1)Oc1ccccc1

InChI Key InChIKey=INUSBZKZIYQSRM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50025988   

TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50025988(1-(2-Phenoxy-ethyl)-1H-imidazole | CHEMBL284827)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthase by bioassay methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50025988(1-(2-Phenoxy-ethyl)-1H-imidazole | CHEMBL284827)
Affinity DataIC50: 660nMAssay Description:Inhibitory activity against thromboxane A2 synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Sheep)
TBA

Curated by ChEMBL
LigandPNGBDBM50025988(1-(2-Phenoxy-ethyl)-1H-imidazole | CHEMBL284827)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of ram seminal vesicle CyclooxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50025988(1-(2-Phenoxy-ethyl)-1H-imidazole | CHEMBL284827)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed