BDBM50025223 CHEMBL343529

SMILES COc1cccc2[nH]cc(CCN)c12

InChI Key InChIKey=WMBARRJMPVVQEZ-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50025223   

TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50025223(CHEMBL343529)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50025223(CHEMBL343529)
Affinity DataEC50: >1.00E+4nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50025223(CHEMBL343529)
Affinity DataEC50:  9nMAssay Description:Agonist activity at 5HT2A receptor (unknown origin) by cell based calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50025223(CHEMBL343529)
Affinity DataIC50: 4.11E+3nMAssay Description:Inhibition of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50025223(CHEMBL343529)
Affinity DataIC50: 220nMAssay Description:Evaluated for inhibition of specific [3H]5-HT receptor binding in rat cortex.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed