BDBM50025040 CHEMBL3355098

SMILES [H][C@]12N3C=C4/[C@]5([H])N(C=C1[C@@]1([H])C[C@@]6([H])[C@@]2(CC[N+]6(Cc2ccc(cc2)[N+]([O-])=O)C[C@H]1CC)c1ccccc31)c1ccccc1[C@@]51CC[N+]2(Cc3ccc(cc3)[N+]([O-])=O)C[C@@H](CC)[C@]4([H])C[C@@]12[H]

InChI Key InChIKey=NVXHMIHJDZFVNO-UHFFFAOYSA-L

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50025040   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50025040(CHEMBL3355098)
Affinity DataIC50: 2.10E+4nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in GH3 cells by Ca2+/Fluo-4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Pig)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50025040(CHEMBL3355098)
Affinity DataEC50:  49nMAssay Description:Displacement of [3H]NMS from pig muscarinic M2 receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50025040(CHEMBL3355098)
Affinity DataIC50: 2.14E+4nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in GH3 cells by Ca2+/Fluo-4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Pig)
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50025040(CHEMBL3355098)
Affinity DataEC50:  49nMAssay Description:Displacement of [3H]NMS from pig muscarinic M2 receptor after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed