BDBM50024573 CHEMBL3330617::US9290463, A

SMILES Cn1c(=O)cnn(CCCCN2CCN(CC2)c2cccc(Br)n2)c1=O

InChI Key InChIKey=VZGYMMOPAWNKDV-UHFFFAOYSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50024573   

Target5-hydroxytryptamine receptor 1A(Human)
Stony Brook University

Curated by ChEMBL

LigandBDBM50024573(US9290463, A | CHEMBL3330617)Copy SMILESCopy InChI

Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/6/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

Target5-hydroxytryptamine receptor 1A/2C(Human)
Columbia University

US Patent

LigandBDBM50024573(US9290463, A | CHEMBL3330617)Copy SMILESCopy InChI

Affinity DataKi:  4nM ΔG°:  -10.6kcal/molepH: 7.4 T: 2°CAssay Description:Preparation of Membrane Fractions from CHO-h5-HT1A Cells. Membranes from CHO cells stably expressing the human 5-HT1A receptor at a density of 8 pmol...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
1/30/2017
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL