BDBM50023706 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-benzoylamino}-3-phosphono-propionic acid::CHEMBL28223

SMILES Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)NC(CP(O)(O)=O)C(O)=O)cnc2n1

InChI Key InChIKey=GELPWSJJLNTEIH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023706   

TargetDihydrofolate reductase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023706(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-ben...)
Affinity DataIC50: 550nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) in mouse L1210 leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed