BDBM50023064 CHEMBL297628::N-{1-[1-[1-Cyclohexylmethyl-2-hydroxy-4-(propane-2-sulfonyl)-butylcarbamoyl]-2-(3H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-3,3-dimethyl-butyramide

SMILES CC(C)S(=O)(=O)CC[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CC(C)(C)C

InChI Key InChIKey=BJWWMAAXHWDCAX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50023064   

TargetRenin(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50023064(N-{1-[1-[1-Cyclohexylmethyl-2-hydroxy-4-(propane-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition against rat plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50023064(N-{1-[1-[1-Cyclohexylmethyl-2-hydroxy-4-(propane-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition against cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50023064(N-{1-[1-[1-Cyclohexylmethyl-2-hydroxy-4-(propane-2...)
Affinity DataIC50: 19nMAssay Description:Inhibition against human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50023064(N-{1-[1-[1-Cyclohexylmethyl-2-hydroxy-4-(propane-2...)
Affinity DataIC50: 6nMAssay Description:Inhibition against purified human renal reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed