BDBM50022851 CHEMBL413534::Pro-His-Pro-Phe-His-Phe-Phe-Val-Tyr-Lys

SMILES CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(O)=O

InChI Key InChIKey=XPAHSKSBHMOJNZ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50022851   

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022851(Pro-His-Pro-Phe-His-Phe-Phe-Val-Tyr-Lys | CHEMBL41...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibitory potency on plasma renin obtained from New Zealand white rabbitsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022851(Pro-His-Pro-Phe-His-Phe-Phe-Val-Tyr-Lys | CHEMBL41...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Human plasma reninMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022851(Pro-His-Pro-Phe-His-Phe-Phe-Val-Tyr-Lys | CHEMBL41...)
Affinity DataIC50: 9.41E+3nMAssay Description:Plasma renin inhibitory activity was evaluated in lyophilized human plasma with 0.1%EDTAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50022851(Pro-His-Pro-Phe-His-Phe-Phe-Val-Tyr-Lys | CHEMBL41...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory activity was evaluated against Angiotensin I converting enzyme activity in rabbitMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022851(Pro-His-Pro-Phe-His-Phe-Phe-Val-Tyr-Lys | CHEMBL41...)
Affinity DataIC50: 9.40E+3nMAssay Description:Compound was tested for inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50022851(Pro-His-Pro-Phe-His-Phe-Phe-Val-Tyr-Lys | CHEMBL41...)
Affinity DataIC50: 1.20E+4nMAssay Description:Compound was tested for inhibition of Angiotensin I converting enzyme from rabbit lung.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022851(Pro-His-Pro-Phe-His-Phe-Phe-Val-Tyr-Lys | CHEMBL41...)
Affinity DataIC50: 8.00E+3nMAssay Description:In vitro inhibitory activity towards porcine kidney reninMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed