BDBM50021448 8-(2-Hydroxy-4-methoxy-phenyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::8-(2-Hydroxy-4-methoxy-phenyl)-1,3-dipropyl-3,9-dihydro-purine-2,6-dione::8-(2-hydroxy-4-methoxyphenyl)xanthine::CHEMBL350469

SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccc(OC)cc1O

InChI Key InChIKey=RQAXETYXJICKOZ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50021448   

TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021448(8-(2-Hydroxy-4-methoxy-phenyl)-1,3-dipropyl-3,7-di...)
Affinity DataKi:  11nMAssay Description:Binding affinity against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50021448(8-(2-Hydroxy-4-methoxy-phenyl)-1,3-dipropyl-3,7-di...)
Affinity DataKi:  46.5nMAssay Description:Binding affinity at human Adenosine A2B receptor expressed in HEK293 cells, using [125I]ABOPX as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021448(8-(2-Hydroxy-4-methoxy-phenyl)-1,3-dipropyl-3,7-di...)
Affinity DataKi:  97.7nMAssay Description:Binding affinity of specific [3H]R-PIA binding to rat Adenosine A1 receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
National Institute of Diabetes, Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50021448(8-(2-Hydroxy-4-methoxy-phenyl)-1,3-dipropyl-3,7-di...)
Affinity DataKi:  180nMAssay Description:Inhibition of 5'-(N-ethylcarbamoyl)adenosine-elicited stimulation of adenylate cyclase in human platelet membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021448(8-(2-Hydroxy-4-methoxy-phenyl)-1,3-dipropyl-3,7-di...)
Affinity DataKi:  980nMAssay Description:Binding affinity against A2 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50021448(8-(2-Hydroxy-4-methoxy-phenyl)-1,3-dipropyl-3,7-di...)
Affinity DataKi:  5.50E+3nMAssay Description:Binding affinity at rat Adenosine A2A receptor by [3H]-CGS- 21680 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed